Uttalelse fra Dr. Vernon om U.K. XMRV-studiet
Suzanne D. Vernon, PhD har kommet med en uttalelse om BBCs oppslag «Research finds no proof that a virus is the cause of ME»
Om Suzanne D. Vernon hentet fra cfids.org: «She earned her doctorate in virology at the University of Wisconsin at Madison and worked in public health research on infectious diseases at the U.S. Centers for Disease Control and Prevention for 17 years before joining the CFIDS Association of America’s staff as scientific director in 2007. She has more than 70 peer-reviewed scientific publications on topics including human immunodeficiency virus, human papillomavirus, cervical cancer and chronic fatigue syndrome. Dr. Vernon has initiated and participated in numerous international and multidisciplinary research collaborations and she now leads the CFIDS Association’s research program. «
Dr. Suzanne D. Vernon skriver:
«Can this study be considered comparable to the results published by Lombardi et al., in Science? In short, no. Both studies included CFS patients defined by the 1994 case definition criteria, but this is where the comparability ends. Here are some of the ways the PLoS ONE and Science methods differ:
- The blood was collected from CFS patients in different types of blood collection tubes.
- The genomic DNA was extracted and purified using different techniques.
- The amount of genomic DNA included in the amplification assay was different.
- Different primer sequences were used that amplified different regions of the XMRV proviral DNA.
- The conditions of the PCR amplification assay were different – from the numbers of cycles, to the type of polymerase used.
Should these differences affect an investigator’s ability to detect XMRV? To a microbiologist with experience handling samples and studying various infectious agents (as I am), these variances in procedure could make the difference between detecting XMRV or not.»
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