Immune system boost cures HIV-like infections
Hentet fra abc.net.au:
«A group of Australian scientists have been able to cure HIV-like infections in mice by boosting their immune systems.
Doctor Marc Pellegrini from Melbourne’s Walter and Eliza Hall Institute found a hormone known as Interleukin 7 stimulates the body’s response to an infection, causing it to clear the virus.
This process is called immune exhaustion.
«We found that Interleukin 7 boosted the immune response in a pretty profound fashion, such that animals were able to gradually clear the virus without too much collateral tissue damage,» Dr Pellegrini said.
«The findings could lead to a cure for chronic viral infections like HIV, hepatitis B and C, and bacterial infections such as tuberculosis.»
The aim of the research was to manipulate the immune system to fight off infection.
«Viruses such as HIV and hepatitis B and C overwhelm the immune system, leading to establishment of chronic infections that are lifelong and incurable,» Dr Pellegrini said.
«Despite tremendous efforts, long-lived immune responses for some of these viruses are ineffective because the body is so overrun by virus that the immune system – in particular T cells – just give up trying to battle the infection.»
The scientists also found that gene SOCS-3 was switched off, which boosted the immune system and allowed the animals to clear the HIV infection.
The findings have been published today in the medical journal Cell.»
Les mer HER